Hatano Taku

HATANO Taku, M.D., Ph.D.

Short Biography

Educational Background
1993-1999	Juntendo University, Faculty of Medicine
2003-2007	The Graduate School of Juntendo University
1999	Received M.D. from Juntendo University Faculty of Medicine
2007	Received Ph.D. from the Graduate School of Juntendo University
Professional Background
1999-2001 2001-2003 2007-2011 2011-2023 2023-2025 2025-	Medical Intern in Juntendo University Hospital Senior Resident (Neurology) in Juntendo University Hospital Assistant Professor in Department of Neurology, Juntendo University Faculty of Medicine Associate Professor in Department of Neurology, Juntendo University Faculty of Medicine Senior Associate Professor in Department of Neurology, Juntendo University Faculty of Medicine Professor and Chair, Department of Neurology, Juntendo University Faculty of Medicine

Key Words

• Parkinson’s Disease
• Atypical Parkinsonism
• Dementia with Lewy Body
• REM Sleep Behavior Disorder
• Alpha-Synuclein
• LRRK2

Main Research Topics

• Biomarker for Neurodegenerative Disorders
• Neuroimaging
• Clinical Trials

Publications (in English)

• Original Articles: 162
• Review Articles: 23
• Books: 5
• Citations: 5,045 (Web of Science)
• H-index: 39 (Web of Science)

Recent Main Publications

• Oji Y, Hatano T, Ueno SI, Funayama M, Ishikawa KI, Okuzumi A, Noda S, Sato S, Satake W, Toda T, Li Y, Hino-Takai T, Kakuta S, Tsunemi T, Yoshino H, Nishioka K, Hattori T, Mizutani Y, Mutoh T, Yokochi F, Ichinose Y, Koh K, Shindo K, Takiyama Y, Hamaguchi T, Yamada M, Farrer MJ, Ushiyama Y, Akamatsu W, Wu YR, Matsuda J, Hattori N: Variants in saposin D domain of prosaposin gene linked to Parkinson’s disease. Brain, 2020, 143: 1190-1205
• Ogawa T, Hatano T, Kamagata K, Andica C, Takeshige-Amano H, Uchida W, Kamiyama D, Shimo Y, Oyama G, Umemura A, Iwamuro H, Ito M, Hori M, Aoki S, Hattori N: White matter and nigral alterations in multiple system atrophy-parkinsonian type. npj Parkinson Dis,  2021; 7: 96
• Okuzumi A, Hatano T, Matsumoto G, Nojiri S, Ueno SI, Imamichi-Tatano Y, Kimura H, Kakuta S, Kondo A, Fukuhara T, Li Y, Funayama M, Saiki S, Taniguchi D, Tsunemi T, McIntyre D, Gérardy JJ, Mittelbronn M, Kruger R, Uchiyama Y, Nukina N, Hattori N. Propagative α-synuclein seeds as serum biomarkers for synucleinopathies. Nat Med, 2023; 29: 1448-1455
• Takeshige-Amano H, Hatano T, Kamagata K, Andica C, Ogawa T, Shindo A, Uchida W, Sako W, Saiki S, Shimo Y, Oyama G, Umemura A, Ito M, Hori M, Aoki S, Hattori N. Free-water diffusion magnetic resonance imaging under selegiline treatment in Parkinson's disease. J Neurol Sci, 2024; 457: 122883
• Hatano T, Oyama G, Shimo Y, Ogaki K, Nishikawa N, Nakamura R, Tsunemi T, Ogawa T, Eguchi H, Daida K, Kurita N, Ueno SI, Fukae J, Sako W, Shiina K, Nakajima S, Oji Y, Wakamori R, Saiki S, Nishioka K, Okuzumi A, Taniguchi D, Takeshige-Amano H, Fuse A, Nakajima A, Kano M, Kamo H, Yamashita Y, Shindo A, Yanagisawa N, Hattori N. Efficacy and Safety of Elobixibat in Parkinson's Disease with Chronic Constipation: CONST-PD Study. Mov Disord Clin Pract, 2024; 11: 352-362
• Furusawa-Nishii E, Solongo B, Rai K, Yoshikawa S, Chiba A, Okuzumi A, Ueno SI, Hoshino Y, Imamichi-Tatano Y, Kimura H, Hatano T, Hattori N, Miyake S: α-Synuclein orchestrates Th17 responses as antigen and adjuvant in Parkinson’s disease. J Neuroinflammation 2025; 22: 38.
  
• More

Recent Main Grant Activities

      2021-2023                                                     Grant-in-Aid for Scientific Research (C), JSPS KAKENHI Grant Number 21K07424

      2024-2026                                                     Grant-in-Aid for Scientific Research (B), JSPS KAKENHI Grant Number 24K02373

       2021-2024                                                     The Japan Agency for Medical Research and Development (AMED) under grant number 24wm0425015

       2024-2026                                                     The Japan Agency for Medical Research and Development (AMED) under grant number 25dk0207072

       2025-2029                                                     The Japan Agency for Medical Research and Development (AMED) under grant number 25wm0625127

Main Awards  

         2020                                                                The Setsuro Fujii Memorial Osaka Foundation for Promotion of Fundamental Medical Research

         2020                                                                Juntendo Academic Encouragement Award

         2023                                                                Juntendo University, GAUDI award Level2

         2023                                                                Grant of Uehara Memorial Foundation

         2024                                                                Japanese Society of Neurology 2024 Award

Link

Department of Neurology