HIOKI Hiroyuki, M.D., Ph.D.
Department of Multi-Scale Brain Structure Imaging
Short Biography
| 2003 | M.D., Kyoto University Faculty of Medicine |
| 2005.01-2017.10 | Assistant Professor, Department of Morphological Brain Science, Kyoto University Graduate School of Medicine |
| 2008 | Ph.D., Kyoto University Graduate School of Medicine |
| 2014.05-Present | Visiting Researcher, RIKEN Center for Brain Science |
| 2017.11-2021.04 | Associate Professor, Juntendo University Faculty of Medicine |
| 2017.11-2020.03 | Part-Time Lecturer, Kyoto University Faculty of Medicine |
| 2019.04-Present | Part-Time Lecturer, The University of Tokyo Faculty of Medicine
Part-Time Lecturer, Hokkaido University Graduate School of Medicine |
| 2020.04-Present | Visiting Researcher, Kyoto University Graduate School of Medicine |
| 2020.10-Present | Visiting Researcher, The Jikei University School of Medicine |
| 2020.11-Present | PI, Department of Multi-Scale Brain Structure Imaging, Juntendo University Graduate School of Medicine (Endowed Research Section) |
| 2021.05-Present | Professor, Department of Cell Biology and Neuroscience, Juntendo University Graduate School of Medicine |
| 2021.07-Present | Professor, Department of Neuroanatomy, Juntendo University Graduate School of Medicine |
Keywords
- Neuronal Circuit
- Central Nervous System
- Neocortex
- Neuroanatomy
- Bioimaging
Main Research Topics and Interests
- Local circuit of the neocortex
- Neuronal circuit analysis of the central nervous system
- Morphological analysis of mouse disease models
- Morphological and physiological plasticity in learning
- Development of innovative bioimaging tools (e.g., virus vectors and tissue-clearing technique)
Publications (in English)
- Original Articles: 76
- Review Articles: 1
- Books: 3
- h-index: 33 (Scopus)
- Sum of Times Cited: 5,081 (Scopus)
Recent Main Publications
- Okamoto S, Yamauchi K, Sohn J, Takahashi M, Ishida Y, Furuta T, Koike M, Fujiyama F, *Hioki H. (2021) Exclusive labeling of direct and indirect pathway neurons in the mouse neostriatum by an adeno-associated virus vector with Cre/lox system. STAR Protoc. 2(1):100230. PMID:33364620, doi:10.1016/j.xpro.2020.100230
- Okamoto K, Ebina T, Fujii N, Konishi K, Sato Y, Kashima T, Nakano R, Hioki H, Takeuchi H, Yumoto J, Matsuzaki M, *Ikegaya Y. (2021) Tb(3+)-doped fluorescent glass for biology. Sci Adv. 7(2):eabd2529. PMID:33523970, doi:10.1126/sciadv.abd252
- Ota K, Oisi Y, Suzuki T, Ikeda M, Ito Y, Ito T, Uwamori H, Kobayashi K, Kobayashi M, Odagawa M, Matsubara C, Kuroiwa Y, Horikoshi M, Matsushita J, Hioki H, Ohkura M, Nakai J, Oizumi M, Miyawaki A, Aonishi T, Ode T, *Murayama M. (2021) Fast, cell-resolution, contiguous-wide two-photon imaging to reveal functional network architectures across multi-modal cortical areas. Neuron. 109(11):1810-1824. PMID:33878295, doi:10.1016/j.neuron.2021.03.032
- Chen S, He L, Huang AJY, Boehringer R, Robert V, Wintzer ME, Polygalov D, Weitemier AZ, Tao Y, Gu M, Middleton SJ, Namiki K, Hama H, Therreau L, Chevaleyre V, Hioki H, Miyawaki A, Piskorowski RA, *McHugh TJ. (2020) A hypothalamic novelty signal modulates hippocampal memory. Nature. 586(7828):270-274. PMID:32999460, doi:10.1038/s41586-020-2771-1
- Katayama H, Hama H, Nagasawa K, Kurokawa H, Sugiyama M, Ando R, Funata M, Yoshida N, Homma M, Nishimura T, Takahashi M, Ishida Y, Hioki H, Tsujihata Y, *Miyawaki A. (2020) Visualizing and Modulating Mitophagy for Therapeutic Studies of Neurodegeneration. Cell. 181(5):1176-1187. PMID:32437660, doi:10.1016/j.cell.2020.04.025
- Okamoto S, Sohn J, Tanaka T, Takahashi M, Ishida Y, Yamauchi K, Koike M, Fujiyama F, *Hioki H. (2020) Overlapping Projections of Neighboring Direct and Indirect Pathway Neostriatal Neurons to Globus Pallidus External Segment. iScience. 23(9):101409. PMID:32877648, doi:10.1016/j.isci.2020.101409
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