KITAURA Jiro, M.D., Ph.D.
Department of Science of Allergy and Inflammation
Short Biography
| 1986-1992 | M.D. Faculty of Medicine, The University of Tokyo |
| 1996-1997 | Assistant Professor, Department of Pediatrics, The University of Tokyo Hospital |
| 1997-2004 | Postdoctoral Fellow, The La Jolla Institute for Allergy and Immunology |
| 2004-2013 | Assistant Professor, Division of Cellular Therapy, The Institute of Medical Science, The University of Tokyo |
| 2013-2014 | Associate Professor, Division of Cellular Therapy, The Institute of Medical Science, The University of Tokyo |
| 2014-Present | Senior Associate Professor, Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine |
Keywords
- Allergy and Inflammation
- Activating and Inhibitory Signaling
- Paired Immune Receptor Family CD300
- IgE and High-affinity IgE Receptor (FcεRI)
- Mast Cell
Main Research Topics and Interests
- Regulatory mechanisms of allergy and inflammation
- Development of therapeutics against allergic/inflammatory diseases
- Analysis of immune receptors (e.g., CD300, FcεRI, MRGPR, and ST2)
- Mast cell biology
- Auto-inflammatory disease
Publications (in English)
- Original Articles: 82
- Review Articles: 8
- h-index: 35
- Sum of Times Cited: 3,568
Recent Main Publications
- Takamori A, Izawa K, Kaitani A, Ando T, Okamoto Y, Maehara A, Tanabe A, Nagamine M, Yamada H, Uchida S, Uchida K, Isobe M, Hatayama T, Watanabe D, Ando T, Ide T, Matsuzawa M, Maeda K, Nakano N, Tamura N, Ikeda K, Ebihara N, Shimizu T, Ogawa H, Okumura K, Kitaura J: Identification of inhibitory mechanisms in pseudo-allergy involving Mrgprb2/MRGPRX2-mediated mast cell activation. J Allergy Clin Immunol. 143: 1231-1235, 2019
- Takahashi M, Izawa K, Urai M, Yamanishi Y, Maehara A, Isobe M, Matsukawa T, Kaitani A, Takamori A, Uchida S, Yamada H, Nagamine M, Ando T, Shimizu T, Ogawa H, Okumura K, Kinjo Y, Kitamura T, Kitaura J: The phytosphingosine-CD300b interaction promotes zymosan-induced, nitric oxide-dependent neutrophil recruitment. Sci Signal. 12: 564, 2019
- Uchida S, Izawa K, Ando T, Yamada H, Uchida K, Negishi N, Kaitani A, Maehara A, Nagamine M, Kamei A, Takamori A, Maeda K, Nakano N, Shimizu T, Ogawa H, Okumura K, Nagahara A, Watanabe S, Kitaura J: CD300f is a potential therapeutic target for the treatment of food allergy. Allergy. 75: 471-474, 2020.
- Yasudo H, Ando T, Maehara A, Ando T, Izawa K, Tanabe A, Kaitani A, Nomura S, Seki M, Yoshida K, Oda H, Okamoto Y, Wang H, Kamei A, Kojima M, Kimura M, Uchida K, Nakano N, Kaneko J, Ebihara N, Hasegawa K, Shimizu T, Takita J, Ogawa H, Okumura K, Ogawa S, Tamura N, Kitaura J: A Possible Association Between a Nucleotide-Binding Domain LRR-Containing Protein Family PYD-Containing Protein 1 Mutation and an Autoinflammatory Disease Involving Liver Cirrhosis. Hepatology. 2021, in press.
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