NAKAMURA Tetsuya, M.D., Ph.D.
Department of Research and Development for Organoids
Short Biography
| 1992 | M.D. Keio University School of Medicine |
| 1997 | Clinical and Research Fellow, Institute of Medical Science, The University of Tokyo |
| 2001 | Research Associate, Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University |
| 2003 | Ph.D. The University of Tokyo |
| 2005 | Visiting Scientist, Cold Spring Harbor Laboratory, NY, USA |
| 2007 | Assistant Professor, Department of Advanced Therapeutics for GI Diseases, Tokyo Medical and Dental University |
| 2012 | Associate Professor, Department of Advanced Therapeutics for GI Diseases, Tokyo Medical and Dental University |
| 2014 | Professor, Department of Advanced Therapeutics for GI Diseases, Tokyo Medical and Dental University |
| 2019 | Professor, Department of Research and Development for Organoids, Juntendo University Graduate School of Medicine |
Keywords
- Intestinal Stem Cells
- Organoid Culture
- Regenerative Medicine
- Gene Expression
- Mucosal Immunology
Main Research Topics and Interests
- Regulation for cellular differentiation and proliferation in the intestinal epithelium
- Regulatory mechanisms of gene expression in intestinal epithelial cells
- Functional interactions between the epithelium and non-epithelial elements in the intestine
- Development of intestinal organoid technology
- Applications of organoids in regenerative medicine
Publications (in English)
- Original Articles: 94
- Review Articles: 6
- h-index: 32 (Web of Science)
- Sum of Times Cited: 4,296 (Web of Science)
Recent Main Publications
- Watanabe S, Nishimura R, Shirasaki T, Katsukura N, Hibiya S, Kirimura S, Negi M, Okamoto R, Matsumoto Y, Nakamura T, Watanabe M, Tsuchiya K. Schlafen 11 is a novel target for mucosal regeneration in Ulcerative Colitis. J Crohns Colitis. 2021 doi: 10.1093/ecco-jcc/jjab032.
- Sugimoto S, Ohta Y, Fujii M, Matano M, Shimokawa M, Nanki K, Date S, Nishikori S, Nakazato Y, Nakamura T, Kanai T, Sato T. Reconstruction of the human colon epithelium in vivo. Cell Stem Cell. 22(2): 171-176: 2018
- Yui S, Azzolin L, Maimets M, Pedersen MT, Fordham RP, Hansen SL, Larsen HL, Guiu J, Alves MRP, Rundsten CF, Johansen JV, Li Y, Madsen CD, Nakamura T, Watanabe M, Nielsen OH, Schweiger PJ, Piccolo S, Jensen KB. YAP/TAZ-dependent reprogramming of colonic epithelisum links ECM remodeling to tissue regeneration. Cell Stem Cell. 22(1): 35-49: 2018
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