OKUMURA Ko, M.D., Ph.D.
Department of Biofunctional Microbiota
Short Biography
| 1969 | M.D. Chiba University School of Medicine |
| 1973 | Ph.D. (Pathology) Chiba University Graduate School of Medicine |
| 1973 | Research Associate, NIH |
| 1974 | Research Fellow, Department of Genetics, Stanford University |
| 1977 | Assistant Professor, Department of Immunology, The University of Tokyo |
| 1979 | Associate Professor, Department of Immunology, The University of Tokyo |
| 1983 | Professor, Department of Immunology, Juntendo University Faculty of Medicine |
| 2000 | Dean, Juntendo University Faculty of Medicine |
| 2008 | Director, Atopy Research Center, Juntendo University Graduate School of Medicine |
Keywords
- Immunology
- Allergy
- Transplantation
- Cancer
- Microbiota
- Probiotics
Main Research Topics and Interests
- Biological function of Microbiota and Probiotics
- Immunological mechanisms of Allergy and Atopy
- Immune responses against cancer
- Immunological tolerance induction in transplantation
Publications in the last 5 years (English)
- Original Articles (50)
Recent Main Publications
- Kojima, Y., Nishina, T., Nakano, H., Okumura, K. and Takeda, K.: Inhibition of Importin β1 Augments the Anticancer Effect of Agonistic Anti-Death Receptor 5 Antibody in TNF-Related Apoptosis-Inducing Ligand-Resistant Tumor Cells. Mol. Cancer Ther. 19 (5): 1123-1133, 2020. DOI: 10.1158/1535-7163.MCT-19-0597
- Takeda, K., Kitaura, K., Suzuki, R., Owada, Y., Muto, S., Okabe, N., Hasegawa, T., Osugi, J., Hoshino, M., Tsunoda, T., Okumura, K., and Suzuki, H.: Quantitative T cell repertoire analysis of peripheral blood mononuclear cells from lung cancer patients following long-term cancer peptide vaccination. Cancer Immunol. Immunother. 67 (6): 946-964, 2018. DOI 10.1007/s00262-018-2152-x.
- Takeda, K., Nakayama, M., Hayakawa, Y., Kojima, Y., Ikeda, H., Naoko Imai, N., Ogasawara, K., Okumura, K., Thomas, D. M. and Smyth, M. J.: IFN-γ is required for cytotoxic T cell-dependent cancer genome immunoediting. Nature Commun. 8: 14607, 2017. DOI: 10.1038/ncomms14607.
- Makino, S., Sato, A., Goto, A., Nakamura, M., Ogawa, M., Chiba, Y., Hemmi, J., Kano, H., Takeda, K., Okumura, K. and Asami, Y.: Enhanced natural killer cell activation by exopolysaccharides derived from yogurt fermented with Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1. J. Dairy Science. 99 (2): 915-923. 2016. doi.org/10.3168/jds.2015-10376
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