Sakamoto Kazuhiro

SAKAMOTO Kazuhiro, M.D., Ph.D.

Short Biography

Keywords

• Colorectal cancer
• Minimally invasive surgery
• Oncology
• Circulating tumor cell (CTC)
• Tumor microenvironment

Main Research Topics and Interests

• Basic and clinical study on laparoscopic surgery
• Genetic study on carcinogenesis of colorectal cancer
• Molecular biological study on metastasis of colorectal cancer
• Clinical study on perioperative surgical stress

Publications (in English)

• Original Articles: 152
• Review Articles: 0
• Books: 1
• h-Index: 14 (Web of Science)
• Sum of Times Cited: 450 (Web of Science)

Recent Main Publications

• Sugimoto K, Ito T, Hulbert A, Chen C, Orita H, Maeda M, Moro H, Fukagawa T, Ushijima T, Katai H, Wada R, Sato K, Sakamoto K, Yu W, Considine M, Cope L, Brock MV. DNA methylation genome-wide analysis in remnant and primary gastric cancers.Gastric Cancer. 2019 Nov;22(6):1109-1120. doi: 10.1007/s10120-019-00949-5.
• Takahashi R, Sakamoto K, Sugimoto K, Motegi S, Tsukamoto R, Ichikawa R, Okazawa Y, Aoki J, Ishiyama S, Takahashi M, Kojima Y, Okuzawa A, Tomiki Y, Masuoka J. Significance of Serum p53 Antibody as a Tumor Marker in Colorectal Cancer Dis Markers. 2019 Dec 14;2019:2721876. doi: 10.1155/2019/2721876. eCollection 2019.
• Mizukoshi K, Okazawa Y, Haeno H, Koyama Y, Sulidan K, Komiyama H, Saeki H, Ohtsuji N, Ito Y, Kojima Y, Goto M, Habu S, Hino O, Sakamoto K, Orimo A. Metastatic seeding of human colon cancer cell clusters expressing the hybrid epithelial/mesenchymal state. Int J Cancer. 2020 May 1;146(9):2547-2562. doi: 10.1002/ijc.32672.
• Tsuchiya Y, Munakata S, Tsukamoto R, Okazawa Y, Mizukoshi K, Sugimoto K, Takahashi M, Tomiki YKY, Sakamoto K. Creatine kinase elevation after robotic surgery for rectal cancer due to a prolonged lithotomy position. BMC Surg. 2020 Jun 16;20(1):136. doi: 10.1186/s12893-020-00771-2.
• Shiosaki J, Tiirikainen M, Peplowska K, Shaeffer D, Machida M, Sakamoto K, Takahashi M, Kojima K, Machi J, Bryant-Greenwood P, Kuwada SK. Serum micro-RNA Identifies Early Stage Colorectal Cancer in a Multi-Ethnic Population. Asian Pac J Cancer Prev. 2020 Oct 1;21(10):3019-3026. doi: 10.31557/APJCP.2020.21.10.3019.
• Okita K, Hara Y, Okura H, Hayashi H, Sasaki Y, Masuko S, Kitadai E, Masuko K, Yoshimoto S, Hayashi N, Sugiura R, Endo Y, Okazaki S, Arai S, Yoshioka T, Matsumoto T, Makino Y, Komiyama H, Sakamoto K, Masuko T. Antitumor effects of novel mAbs against cationic amino acid transporter 1 (CAT1) on human CRC with amplified CAT1 gene. Cancer Sci. 2020 Nov 19. doi: 10.1111/cas.14741.
• Kure K, Hosoya M, Ueyama T, Fukaya M, Sugimoto K, Tomiki Y, Ohnaga T, Sakamoto K, Komiyama H. Using the polymeric circulating tumor cell chip to capture circulating tumor cells in blood samples of patients with colorectal cancer. Oncol Lett. 2020 Mar;19(3):2286-2294. doi: 10.3892/ol.2020.11335. Epub 2020 Jan 23.
• Yamada T, Endo H, Hasegawa H, Kimura T, Kakeji K, Koda K, Ishida H, Sakamoto K, Hirata K, Yamamoto H, Miyata M, Matsuda A, Yoshida H, Kitagawa Y. Risk of emergency surgery for complicated appendicitis: Japanese nationwide study Ann Gastroenterol Surg. 2021;5: 236–242. DOI: 10.1002/ags3.12408
• Sugimoto K, Sakamoto K, Ii Y, Amemiya K, Sugo H, Ito T, Munakata S, Takahashi M, Kojima Y, Tomiki Y, Sato K, Saiura A, Kawasaki S. Significance of postoperative adjuvant chemotherapy with an oxaliplatin-based regimen after simultaneous curative resection for colorectal cancer and synchronous colorectal liver metastasis: a propensity score matching analysis. BMC Surg. 2021 Apr 9;21(1):188. doi: 10.1186/s12893-021-01193-4.PMID: 33836701
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