SAKAMOTO Kazuhiro, M.D., Ph.D.
Department of Coloproctological Surgery
Short Biography
| 1979-1984 | M.D. Juntendo University Faculty of Medicine |
| 1988 | Board Certified Japanese Surgical Society |
| 2005 | Board Certified Japanese Society for Endoscopic Surgery |
| 1984-1986 | Surgical Resident, Juntendo University Hospital and affiliated Hospitals |
| 1986-1995 | Surgical Staff, Department of First Surgery, Juntendo University |
| 1996-2003 | Assistant Professor, Department of First Surgery, Juntendo University Faculty of Medicine |
| 2003-2006 | Assistant Professor, Department of Coloproctological Surgery, Juntendo University Faculty of Medicine |
| 2006-2008 | Associate Professor, Department of Coloproctological Surgery, Juntendo University Faculty of Medicine |
| 2009-Present | Professor, Department of Coloproctological Surgery, Juntendo University Faculty of Medicine |
Keywords
- Colorectal cancer
- Minimally invasive surgery
- Oncology
- Circulating tumor cell (CTC)
- Tumor microenvironment
Main Research Topics and Interests
- Basic and clinical study on laparoscopic surgery
- Genetic study on carcinogenesis of colorectal cancer
- Molecular biological study on metastasis of colorectal cancer
- Clinical study on perioperative surgical stress
Publications (in English)
- Original Articles: 152
- Review Articles: 0
- Books: 1
- h-Index: 14 (Web of Science)
- Sum of Times Cited: 450 (Web of Science)
Recent Main Publications
- Sugimoto K, Ito T, Hulbert A, Chen C, Orita H, Maeda M, Moro H, Fukagawa T, Ushijima T, Katai H, Wada R, Sato K, Sakamoto K, Yu W, Considine M, Cope L, Brock MV. DNA methylation genome-wide analysis in remnant and primary gastric cancers.Gastric Cancer. 2019 Nov;22(6):1109-1120. doi: 10.1007/s10120-019-00949-5.
- Takahashi R, Sakamoto K, Sugimoto K, Motegi S, Tsukamoto R, Ichikawa R, Okazawa Y, Aoki J, Ishiyama S, Takahashi M, Kojima Y, Okuzawa A, Tomiki Y, Masuoka J. Significance of Serum p53 Antibody as a Tumor Marker in Colorectal Cancer Dis Markers. 2019 Dec 14;2019:2721876. doi: 10.1155/2019/2721876. eCollection 2019.
- Mizukoshi K, Okazawa Y, Haeno H, Koyama Y, Sulidan K, Komiyama H, Saeki H, Ohtsuji N, Ito Y, Kojima Y, Goto M, Habu S, Hino O, Sakamoto K, Orimo A. Metastatic seeding of human colon cancer cell clusters expressing the hybrid epithelial/mesenchymal state. Int J Cancer. 2020 May 1;146(9):2547-2562. doi: 10.1002/ijc.32672.
- Tsuchiya Y, Munakata S, Tsukamoto R, Okazawa Y, Mizukoshi K, Sugimoto K, Takahashi M, Tomiki YKY, Sakamoto K. Creatine kinase elevation after robotic surgery for rectal cancer due to a prolonged lithotomy position. BMC Surg. 2020 Jun 16;20(1):136. doi: 10.1186/s12893-020-00771-2.
- Shiosaki J, Tiirikainen M, Peplowska K, Shaeffer D, Machida M, Sakamoto K, Takahashi M, Kojima K, Machi J, Bryant-Greenwood P, Kuwada SK. Serum micro-RNA Identifies Early Stage Colorectal Cancer in a Multi-Ethnic Population. Asian Pac J Cancer Prev. 2020 Oct 1;21(10):3019-3026. doi: 10.31557/APJCP.2020.21.10.3019.
- Okita K, Hara Y, Okura H, Hayashi H, Sasaki Y, Masuko S, Kitadai E, Masuko K, Yoshimoto S, Hayashi N, Sugiura R, Endo Y, Okazaki S, Arai S, Yoshioka T, Matsumoto T, Makino Y, Komiyama H, Sakamoto K, Masuko T. Antitumor effects of novel mAbs against cationic amino acid transporter 1 (CAT1) on human CRC with amplified CAT1 gene. Cancer Sci. 2020 Nov 19. doi: 10.1111/cas.14741.
- Kure K, Hosoya M, Ueyama T, Fukaya M, Sugimoto K, Tomiki Y, Ohnaga T, Sakamoto K, Komiyama H. Using the polymeric circulating tumor cell chip to capture circulating tumor cells in blood samples of patients with colorectal cancer. Oncol Lett. 2020 Mar;19(3):2286-2294. doi: 10.3892/ol.2020.11335. Epub 2020 Jan 23.
- Yamada T, Endo H, Hasegawa H, Kimura T, Kakeji K, Koda K, Ishida H, Sakamoto K, Hirata K, Yamamoto H, Miyata M, Matsuda A, Yoshida H, Kitagawa Y. Risk of emergency surgery for complicated appendicitis: Japanese nationwide study Ann Gastroenterol Surg. 2021;5: 236–242. DOI: 10.1002/ags3.12408
- Sugimoto K, Sakamoto K, Ii Y, Amemiya K, Sugo H, Ito T, Munakata S, Takahashi M, Kojima Y, Tomiki Y, Sato K, Saiura A, Kawasaki S. Significance of postoperative adjuvant chemotherapy with an oxaliplatin-based regimen after simultaneous curative resection for colorectal cancer and synchronous colorectal liver metastasis: a propensity score matching analysis. BMC Surg. 2021 Apr 9;21(1):188. doi: 10.1186/s12893-021-01193-4.PMID: 33836701
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